MB BS BSc (Hons) PhD FRCS (Gen. Surg.)
General Surgeon
24 years of experience
Southampton, SO16 6UY
(+2 more)
36 connections in healthcare
Skill endorsed
by Mr Benjamin Stubbs, Professor James Patrick Byrne and 3 other professionals
24 years of experience
Southampton, SO16 6UY
(+2 more)
36 connections in healthcare
Skill endorsed
by Mr Benjamin Stubbs, Professor James Patrick Byrne and 3 other professionals
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Mr Fergus Noble is an experienced Consultant Upper Gastrointestinal and General Surgeon with a reputation for clinical excellence and patient-centred care. He brings extensive surgical expertise, offering advanced treatment options tailored to each individual’s needs. He is a Consultant in Upper Gastrointestinal and General Surgery at University Hospital Southampton NHS Foundation Trust, and the clinical service lead for Upper Gastrointestinal Surgery, his special interests include the following:
Known for a meticulous approach and clear communication, Mr Noble works closely with each patient to ensure they are informed, confident and fully supported throughout their care.
Trained at St Bartholomew’s and The Royal London Medical School, followed by surgical training in London and Wessex, including a PhD researching immunotherapy and cancer vaccines, and culminating in a prestigious international fellowship at the Royal Adelaide Hospital in Australia, Mr Noble stays at the forefront of surgical innovation.
Most recently, Mr Noble has supported the introduction of robotic oesophageal and gastric surgery at the University Hospital Southampton NHS Foundation Trust. He has also introduced new techniques for anti-reflux surgery into his practice, including the Refluxstop and Linx procedure. Whether managing routine procedures or complex surgical challenges, combining cutting-edge techniques with a commitment to safety, comfort, and optimal recovery ensures that every patient receives the best care to suit their individual needs.
Surgical outcomes are assessed both within and externally to the hospitals and can be reviewed via the National Oesophagogastric Audit and the National Hiatal Registry. Further authored work can be found here in book chapters and peer-reviewed publications.
Philosophy of care: “I believe that whilst Surgery undoubtedly requires technical skill, delivering great care is more than just a procedure. It’s about treating each patient as an individual, building trust and being transparent about options available, and exploring the best treatment plan for you. I’m here to listen to your concerns, answer your questions on the treatments available, and work with you to deliver care that enables you to live a healthier and happier life”
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General Medical Council
No. 6040316
Royal College of Surgeons
No. 1009818
University of Southampton
PhD - Oesophageal Cancer: strategies to improve outcomes, and identify novel immunological biomarkers and targets.
Graduated 2015
Queen Mary, University of London
Medicine
Graduated 2002
Queen Mary, University of London
Experimental Pathology
Graduated 1998
JAG Accreditation in Upper GI Endoscopy
Read publications and papers written by this specialist.
12 / 01 / 2014
Training in laparoscopic total extra-peritoneal hernia repair: Safe under experienced supervision with significant performance improvement
Published in International Journal of Surgery
04 / 12 / 2017
Hiatal Hernia After Esophagectomy for Cancer.
Published in The Annals of Thoracic Surgery
01 / 11 / 2015
Gallstones
Published in Medicine
(553)
Winchester Road, Chandlers Ford, Eastleigh, United Kingdom, SO53 2DW
(0)
Trust Management Offices Mailpoint 18 Southampton General Hospital Tremona Road Southampton, Hampshire, United Kingdom, SO16 6YD
Good experience Everything explained Condition is on going Have another appointment in a months time
As always, Mr Noble was comforting, knowledgeable, patient and understanding.
The Spire outpatients reception was a bit chaotic but not a problem.

Thank you. I agree. The team are aware and resolving.
Excellent explanations, no rush, took time to understand me and ensure my questions were answered fully. No unnecessary medical jargon where it could be avoided. Listened and made sure he understood any concerns.
Mr Noble was very professional gave a good explanation of what the issue was, how it can be treated with all possible side effects and gave great aftercare. I would highly recommend Mr Noble
Today was a follow up to my surgery. Had a phone call telling me level g due to recent fire. All went smoothly whilst there.
I had an excellent experience with Mr. Noble and his team. He explored all treatment options with me ahead of us deciding on a course of action and remained available for any and all questions / concerns during my post-op recovery period. Very pleased with the outcome!
Specialist UGI surgeon. Trusted and experienced.
23 Feb 2026
Mr Benjamin Stubbs
General SurgeonFergus is a great colleague and excellent clinician, who offers wise counsel to patients and colleagues alike. He is assiduous and detailed in his approach to all clinical and operative work.
23 Feb 2026
Professor James Patrick Byrne
General Surgeon
Dr Thomas Hollingworth
Gastroenterologist
Mr Mohamed Rabie
General SurgeonExplore videos from Mr Fergus Noble explaining process of procedures and other important things you should know before choosing your provider.

News Article on Reflux
14 October 2025

On Wednesday 13th November 2024 we were delighted that Fergus Noble, Gastrointestinal Surgeon from Southampton Hospital, kindly agreed to talk about the surg...
14 October 2025
youtube.com

See the first RefluxStop™ case at University Hospital Southampton NHS FT on ITV! Consultant general and oesophageal surgeon, Mr. Fergus Noble completed the procedure.
14 October 2025
youtube.com

Surgeons at University Hospital Southampton face complex surgery to remove a cancerous oesophagus.
17 April 0024
bbc.co.uk

ITV news
18 June 2024
itv.com
Read articles from Mr Fergus Noble explaining process of procedures and other important things you should know before choosing your provider.

Management of gallstones
01 November 2015
medicinejournal.co.uk

Groin Hernia Repair
01 November 2014
sciencedirect.com

Danielle Harding experiences "amazing" results after suffering with severe acid reflux.
18 June 2024
bbc.co.uk

Danielle Harding, and consultant general and oesophagogastric surgeon at UHS Fergus Noble. Danielle Harding, 30, is the […]
21 October 2025
opa.org.uk
What are Mr Fergus Noble's reviews like?
Mr Fergus Noble's overall patient rating is 5 out of 5 stars on Doctify. This is based on 13 reviews.
What languages does Mr Fergus Noble speak?
Mr Fergus Noble speaks English
Where is Mr Fergus Noble located?
Mr Fergus Noble primarily practices at Spire Southampton Hospital, located at Chalybeate Close, Southampton, United Kingdom, SO16 6UY
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What are Mr Fergus Noble working hours?
Mr Fergus Noble is working Monday (09:00 - 12:00), Wednesday (09:00 - 12:00), Thursday (08:30 - 12:30)
Find where Mr Fergus Noble operates today
Does Mr Fergus Noble accept new patients?
Mr Fergus Noble generally accepts new patients.
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