BSc (Hons), Med.Sci., MBChB, MD, FRCS
36 years of experience
Southampton, SO16 6UY
(+2 more)
10 connections in healthcare
Skill endorsed
by Professor Richard Welbourn, Mr Fergus Noble and 1 other professional
36 years of experience
Southampton, SO16 6UY
(+2 more)
10 connections in healthcare
Skill endorsed
by Professor Richard Welbourn, Mr Fergus Noble and 1 other professional
Areas of expertise
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Professor James Byrne is a general and bariatric surgeon practicing at Nuffield Health Wessex Hospital and Spire Southampton Hospital. He completed a BSc in Medical Sciences (Honours) in Physiology at the University of St Andrews in 1986, followed by his medical degree (MB ChB) from the University of Manchester Medical School in 1989. He was awarded an MD by the University of Manchester in 1998.
Professor Byrne was appointed Consultant Surgeon at University Hospital Southampton in 2002, following surgical training in the North West of England and completion of a fellowship at the Princess Alexandra Hospital in Brisbane, Australia. In parallel with his clinical role, he serves as an Honorary Senior Lecturer at the University of Southampton.
His specialist practice includes bariatric and weight loss surgery, upper gastrointestinal surgery, hiatus hernia, and conditions affecting the oesophagus and stomach, including malignancy. He also performs a wide range of laparoscopic procedures, including cholecystectomy, hernia repair, and anti-reflux surgery. Professor Byrne has been a long-standing member of the Southampton bariatric surgical team, which has performed more than 2,000 bariatric procedures since its establishment in 2004.
Outside of clinical practice, his interests include walking, sailing, golf, skiing, and reading.
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General Medical Council
No. 3328736
St. Andrew's University
Medicine
Graduated 1986
University of Manchester
Medicine
Graduated 1989
Royal College of Surgeons
Surgery
Graduated 1994
University of Manchester
Research degree and thesis
Graduated 1997
MB ChB 1989 University of Manchester
MD 1998
BSc(Hons) 1986 Medical Sciences, University of St Andrews
Read publications and papers written by this specialist.
01 / 01 / 2026
A Randomized, Double‐Blind, Placebo‐Controlled Pilot Trial With Open‐Label Extension of Sirona, a Hydrogel for Weight Loss
Published in Obesity
01 / 06 / 2025
Roux-en-Y gastric bypass, adjustable gastric banding, or sleeve gastrectomy for severe obesity (By-Band-Sleeve): a multicentre, open label, three-group, randomised controlled trial
Published in Lancet Diabetes
New appointment
£250Follow-up appointment
£180Chalybeate Close, Southampton, United Kingdom, SO16 6UY
Winchester Road, Chandlers Ford, Eastleigh, United Kingdom, SO53 2DW
Trust Management Offices Mailpoint 18 Southampton General Hospital Tremona Road Southampton, Hampshire, United Kingdom, SO16 6YD
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Dr Byrne was excellent. Really informative about the procedure and explained the process. He was able to provide plenty of support and reassurance regarding the op.
Professor James had thoroughly read my history and was obviously the right person to speak to. His diagnosis and referral were top notch
Extremely happy with the care from both Lisa and Professor Byrne. Thank you both for your friendly and professional service, it was very much appreciated.
I could not be more impressed with the standard f care and level of professionalism I received with Pr Byrne. He took the proper time to listen to me and work efficiently to put together a plan for me. I could not be happier
All round it was very good experience with everybody very pleasant and very helpful.
I felt listened to properly assessed and care for my pain & desperate need for help after months of getter no tests to deal with my problems. I feel less depressed and hopeful that my symptoms will be resolved.
Excellent, very informative, explained various scenarios clearly
Experience was exceptional from start to finish. Professor Byrne made me feel very at ease and relaxed before/after the operation. His attention to detail was excellent. Having not had much surgery done before, the professional approach I received from Professor Byrne was very impressive and I highly commend his work. Thanks again.
I had a very positive experience. The procedure was clearly explained to me, and what I could in regards to recovery. Overall this left me very reassured before and following the procedure
I have nothing but good things to say about my experience, Professor James Byrne made me feel comfortable and confident about the whole thing

Professor Richard Welbourn
General SurgeonHaving worked alongside Prof Byrne, a senior leader in bariatric surgery, he provides a commitment to clinical excellence and compassionate care in general and Upper GI surgery.
26 Feb 2026
Mr Fergus Noble
General Surgeon
Dr Thomas Hollingworth
Gastroenterologist
What are Professor James Patrick Byrne's reviews like?
Professor James Patrick Byrne's overall patient rating is 5 out of 5 stars on Doctify. This is based on 19 reviews.
What languages does Professor James Patrick Byrne speak?
Professor James Patrick Byrne speaks English
Where is Professor James Patrick Byrne located?
Professor James Patrick Byrne primarily practices at Spire Southampton Hospital, located at Chalybeate Close, Southampton, United Kingdom, SO16 6UY
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Does Professor James Patrick Byrne accept new patients?
Professor James Patrick Byrne generally accepts new patients.
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