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Professor Plaha is a Consultant Neuro-oncology surgeon and Associate Professor of Neurosurgery at the University of Oxford. He sub-specialises in brain tumour surgery undertaking complex surgery. 

Since August 2012, Prof Plaha has been a consultant neurosurgeon at the John Radcliffe Oxford University Hospitals. Prof Plaha is Lead of Oxford Neuro oncology MDT since August 2012 and Lead for the Thames valley Cancer network for Brain tumours. Prof Plaha is chair of the Neuro oncology section for the Society of British Neurological Surgeons since 2019. 

 Prof Plaha has developed new techniques for minimally invasive endoscopic resection of brain tumours.  He has extensive experience in awake brain tumour surgery and has established advanced techniques for awake brain tumour surgery. Prof Plaha operates privately at the Wellington Hospital, London with a dedicated team of neuro anaesthetist, neurophysiologist and neurotheatre team. 

Prof Plaha operates jointly with his colleague Mr Vas Apostolopoulos, consultant neuro oncology surgeon.

 Prof Plaha has performed more than 1000 brain tumour operations and is amongst surgeons with a high number of awake operations/year in the UK. Prof Plaha regularly asked to offer second opinion for complex brain tumours patients nationally and internationally.  

 Prof Plaha leads the Oxford surgical neuro oncology research group understanding neural networks affected by brain tumours, looking into novel surgical modalities which make brain surgery safer, understanding immunotherapy for brain tumours and novels clinical trials for brain cancer. 

 Prof Plaha is presently Chief Investigator for the multi centre UK NIHR funded FUTURE-GB trial looking at new surgical technologies for glioblastoma to improve their quality of life and minimise surgical morbidity. 

Prof Plaha has published extensively on brain tumour research and is invited to speak at international conferences.