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Dr Michelagnoli is a trained paediatrician with sub-specialist recognition in paediatric oncology. Her cancer training was carried out in the Yorkshire Regional Department of Paediatric Oncology and haematology. She currently works within the children's and young people cancer service at University College Hospital (CYPCS), site-specialising within the sarcoma service.

Dr Michelagnoli completed her MD (University of Leeds) at the Candlelighter's laboratory (CRUK, Leeds) in the application of molecular diagnostics in rhabdomyosarcoma.

She is chair of the service development group for Teenage and Young Adults with Cancer (TYAC) group - a professional group for specialists in young people's cancer care and she regularly teaches and lectures on the management of sarcomas in children and adolescents, as well as generic lecturing on aspects of adolescent cancer care.