Dr Alastair O'Brien
MBBS BSc FRCP PhD
32 years of experience
Belgravia, SW1X 7HY
(+2 more)
21 connections in healthcare
Skill endorsed
by Dr Bhavna Jaiswal, Mr James Smellie and 2 other professionals
32 years of experience
Belgravia, SW1X 7HY
(+2 more)
21 connections in healthcare
Skill endorsed
by Dr Bhavna Jaiswal, Mr James Smellie and 2 other professionals
Areas of expertise
Contact
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About Dr Alastair O'Brien
Dr Dr Alastair O'Brien is a Consultant Hepatologist specialising in Hepato Pancreato Biliary Medicine.
After qualifying from Guys and St Thomas' Medical School in 1994, he completed gastroenterology and general medicine training on the South Thames rotation. Following this, he undertook his hepatology training at King's College, The Royal London and University College London Hospitals (UCLH). He was a Medical Research Council clinical training fellow at University College London and was awarded a PhD for his research into the use of terlipressin as rescue therapy for septic shock.
In 2007, Dr O'Brien was appointed as Consultant and Clinical Senior Lecturer in Hepatology at UCLH and The Royal Free Hospitals. At ULCH he is responsible for the inpatient management of all causes of acute and chronic liver disease. He runs an outpatients clinic at the Royal Free Hospital and sees patients with non-alcoholic fatty liver disease, autoimmune hepatitis, primary biliary cirrhosis, viral hepatitis (B & C), metabolic and alcohol related liver disease. He also has extensive experience in upper GI endoscopy especially management of variceal bleeding.
Dr O'Brien has been published in a number of leading journals including Nature Medicine, The Lancet, Gastroenterology, Hepatology and Proceedings of The National Academy of Science. He was recently awarded funding for £1.6million by the Wellcome Trust and Department of Health to build a multi-centre clinical trial to prevent infection in cirrhosis patients. He has also gained funding from the Medical Research Council, The UCLH Biomedical Research Centre, and Industry (Pfizer).
Diseases, Medical Tests and Treatments
- Colonoscopy
- Endoscopy
- Gastroscopy
- Liver Biopsy
- Sigmoidoscopy
- Automimmune Hepatitis
- Cirrhosis
- Fatty Liver Disease
- Gallstones
- Hepatitis
- Liver Disease
- Irritable Bowel Syndrome
Subspecialties
- Gastroenterology
Areas of expertise
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Registered with
General Medical Council
No. 4127620
Education
University of London
Medicine
Graduated 1994
Qualifications
MBBS Guy's & St Thomas' Hospitals 1994
BSc Guy's & St Thomas' Hospitals 1991
Membership The Royal College of Physicians (London) 1997
PhD University of London 2005
Fellowship The Royal College of Physicians (London) 2016
Languages spoken
- English
Insurers
- Bupa Fee Assured
- Bupa
- AXA Health
Fees
New appointment
£345Follow-up appointment
£260
Locations
Cleveland Clinic London
33 Grosvenor Place, Belgravia, United Kingdom, SW1X 7HY
Opening hours
Facilities
Opening hours
Facilities
Cleveland Clinic Portland Place Outpatient Centre
24 Portland Pl, London, United Kingdom, W1B 1LU
Opening hours
Cleveland Clinic Moorgate Outpatient Centre
Cleveland Clinic Moorgate Outpatient Centre, 55 Moorgate, London, United Kingdom, EC2R 6BH
Areas of expertise
Contact
Book
Reviews
The doctor was very friendly, did not rush me, provided clear information, and answered all my questions thoroughly.
Professor Alastair O Brien was fantastic. He got straight to the point and informed me of my condition and how that would affect me going forward over the coming months. He surgessed l ask my Liver consultant in Bedford NHS trust hospital to refer me to Addenbrooks Hospital where he could my a referral to go on to the liver transplant list. He even offered to call my liver consultant to ask him to put me on the liver transplant assessment
Professor O’Brien was warm, knowledgeable and extremely helpful. He was aware in advance of my very specific need and I felt extremely confident in his diagnosis and treatment plan. Thank you.
Prof. O'Brien was very welcoming and made sure I am at ease from the beginning of the consultation. He was very attentive to my concerns and clearly explained everything while also responding all of the questions. I highly recommend Prof. O'Brien to anyone with any liver issues.
Dr O’Brien was reassuring whilst acknowledging my concerns and let me know the results of different tests very quickly. He explained the issues in easily understandable language and was happy to answer all my questions.
Dr O’Brien was excellent, put me at ease, explained things clearly and very patient with my questions
It was a pleasure to meet Dr O'Brien. I very much enjoyed the overall level of service, personalised approach and corresponding level of advice as well as suggested next steps.
I recently had the privilege of meeting with Dr Alastair O'Brien , and the experience was truly remarkable. Not only was the Professor incredibly knowledgeable and thorough, but also the most charismatic and medical professional I've ever encountered. I felt genuinely cared for and confident in the path forward. A rare combination of brilliance and charm, an absolute standout in their field. T
Skill Endorsements
General (Internal) Medicine Specialist
27 Aug 2026
Dr Bhavna Jaiswal
PsychologistVery good doctor, I send patients to him and value his opinion.
13 Jan 2025
Mr James Smellie
General SurgeonAlastair combines his clinical knowledge with kindness, skill and dedication. An excellent physician
16 Jun 2024
Professor Ruth Whitby
General Practitionerextremely knowledgeable clinician and excellent colleague
12 Jun 2024
Mr Charles Imber
General SurgeonFAQ
What are Dr Alastair O'Brien's reviews like?
Dr Alastair O'Brien's overall patient rating is 5 out of 5 stars on Doctify. This is based on 17 reviews.
What languages does Dr Alastair O'Brien speak?
Dr Alastair O'Brien speaks English
Where is Dr Alastair O'Brien located?
Dr Alastair O'Brien primarily practices at Cleveland Clinic London, located at 33 Grosvenor Place, Belgravia, United Kingdom, SW1X 7HY
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What are Dr Alastair O'Brien working hours?
Dr Alastair O'Brien is working Tuesday (16:00 - 20:00), Saturday (08:00 - 12:00)
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Does Dr Alastair O'Brien accept new patients?
Dr Alastair O'Brien generally accepts new patients.
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