Dr Paul Brennan

Dr Paul Brennan

BMedSci(Hons), MBBS, FRCP

Clinical Genetics

27 years of experience
18 years as a specialist

Overall Rating

Overall
5
Bedside Manner
5
Explanation
5

Top feedback

“Dr. Brennan was the first positive experience of a medical professional that I've had in over 12 years. He listened to my concerns, validated them and took me seriously. He provided clear explanations for my chronic symptoms, and advised on the necessary investigations to confirm a diagnosis and manage potential risk. I finally have the correct explanation for my difficulties (though more research Is needed!) and a treatment plan to ensure that I get the right care to manage my conditions moving forwards. I can't thank you enough, and I'm sure I will be in contact again for more advice in the future. “
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Languages spoken

  • English
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Registered with

General Medical Council: 3677959

Consultation fees

New appointment: £350

Follow-up appointment: £250

Practices worked at

Harley Street Diagnostic Centre

United Kingdom
9 reviews

CosmeSurge

51 Harley Street, London, United Kingdom, W1G 8QQ
52 reviews

The Northern Genetics Service

Central Parkway, Institute for Genetic Medicine, Newcastle upon Tyne, UK, NE1 3BZ
2 reviews

The Teesside Genetics Unit

Marton Road, James Cook University Hospital, Middlesbrough, UK, TS4 3BW
2 reviews

About

Dr Brennan's main areas of expertise are cancer, cardiac and endocrine genetics.

His interest in genetics started as a medical student in the 1980s when the medical speciality of clinical genetics was in its infancy. After a research degree studying genes in the developing heart, he completed his medical training and undertook postgraduate training in adult medicine and paediatrics before specialist training in Clinical Genetics.

Dr Brennan was appointed as an NHS Consultant in Clinical Genetics in 2002 with the Northern Genetics Service based in Newcastle upon Tyne. After opening a new satellite clinical genetics department in Middlesbrough, he was appointed to the role of Clinical Director of the Northern Genetics Service in 2008, managing a clinical and laboratory team providing genetics diagnostics for the population of North East England and North Cumbria.

Dr Brennan has been Clinical Lead for Cardiac and Endocrine Genetics for the Northern Genetics Service since 2003; he was Clinical Lead for Cancer Genetics 2002 to 2020. 

A particular interest is the use of new technology and novel clinical pathways to improve diagnosis and management for people living with rare inherited disease. Between 2014 and 2018 he was Clinical Programme Director for the North East & North Cumbria NHS Genomic Medicine Centre, overseeing the introduction of whole genome sequencing into routine care as part of the 100,000 Genomes Project. He is engaged in a number of collaborative research projects, all of which are focused on improving diagnosis and treatment.

Dr Brennan is a keen and popular teacher and lectures to a wide range of undergraduate and postgraduate audiences in the UK and overseas. He teaches genetics for a week each year at Newcastle University's Medical School in Malaysia.

www.genomics.expert

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Special interests

Dr Brennan has a long experience of diagnosing and managing hereditary diseases in adults and young people. In general his specialist areas are:


A. Inherited cardiovascular disorders, for example:

  • Brugada syndrome
  • Long QT syndrome
  • Familial hypertrophic and dilated cardiomyopathy
  • Arrhythmogenic right ventricular cardiomyopathy
  • Sudden unexplained death
  • Familial thoracic aortic aneurysm
  • Marfan syndrome, Loeys Dietz syndrome and Meester-Loeys syndrome
  • Vascular Ehlers Danlos syndrome

B. Inherited connective tissue disorders, including

  • classical Ehlers Danlos syndrome
  • hypermobile Ehlers Danlos syndrome

C. Inherited cancer syndromes, for example:

  • Hereditary breast/ovarian cancer
  • Cowden's disease
  • Lynch syndrome
  • Familial Adenomatous Polyposis
  • Hereditary leiomyomatosis / renal cell carcinoma syndrome
  • Birt Hogg Dube syndrome
  • Li Fraumeni syndrome

C. Inherited endocrine syndromes, for example:

  • Familial paragangliomatosis
  • Von Hippel Lindau disease
  • Multiple endocrine neoplasis types 1 & 2 and familial medullary thyroid cancer)
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Education

  • Bachelor of Medical Science (Human Genetics) Newcastle University
  • Bachelor of Medicine and Bachelor of Surgery, Newcastle University

Professional Qualifications:

  • MRCP (Edinburgh)
  • FRCP (London)
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Reviews

Overall
5
Explanation
5
Bedside Manner
5

Dr. Brennan was the first positive experience of a medical professional that I've had in over 12 years. He listened to my concerns, validated them and took me seriously. He provided clear explanations for my chronic symptoms, and advised on the necessary investigations to confirm a diagnosis and manage potential risk. I finally have the correct explanation for my difficulties (though more research Is needed!) and a treatment plan to ensure that I get the right care to manage my conditions moving forwards. I can't thank you enough, and I'm sure I will be in contact again for more advice in the future.

Patient seen for:
Ehlers-Danlos Syndrome (EDS)
05-08-2020
Overall
5
Explanation
5
Bedside Manner
5

My two children and I saw Dr Brennan for assessment of hEDS. I found Dr Brennan extremely thorough and knowledgeable- and he was able to also engage our autistic son well. Dr Brennan had a good understanding of the difficulties we faced as a family unit and provided reassurance and validation. A very nice doctor to see - we would highly recommend.

23-07-2020
Overall
5
Explanation
5
Bedside Manner
5

Highly recommended- We travelled as a family from Northern Ireland to Dr Brennan’s London clinic, in regard to our 17 year old son. Dr Brennan immediately put us at ease and was extremely patient as he listened to an extensive medical history and summary of our journeys towards diagnoses, including my own diagnosis of Ehlers-Danlos Syndrome (EDS). Dr Brennan examined our son and made a clinical diagnosis of hEDS. We arranged a further appointment for our 14 year old daughter and we experienced the same level of professionalism. Once again there was a diagnosis of hEDS; followed by a comprehensive report for us to share with our health professionals. We really appreciated his kind and caring approach and would highly recommend Dr Brennan to anyone concerned that they may have EDS.

Patient seen for:
Ehlers-Danlos Syndrome (EDS)
29-05-2020
Overall
5
Explanation
5
Bedside Manner
5

Dr Brennan is a very professional and kind person. Highly recommended

Patient seen for:
Genetic Consultation
17-05-2020
Overall
5
Explanation
5
Bedside Manner
5

I saw Dr Brennan to get his expert opinion on what I thought was probably hypermobile Ehlers-Danlos Syndrome but had been severely invalidated by numerous NHS specialist teams I've seen. I'm very complex (or a few others might say "complicated") and have signifiant history of mental health issues. I am aware EDS is notoriously hard to get validated as a diagnosis, but because of my MH issues, specialists were even more keen to conclude "its in your head because of you past traumas". I am still on a diagnostic journey with my different specialists trying to get them on board with my physical problems being linked to EDS, its only the mere start but thanks to Dr Brennan's specialist knowledge and excellent clinic letter this is really going to help on this complicated journey! Dr Brennan is very caring, validating and very knowledgeable. His clinic letter was so refreshing that unlike all other clinic letters didn't start off going off on one about my "significant mental health issues".... Thank you for the validation I so desperately needed! Life changing. Literally!

Patient seen for:
Ehlers-Danlos Syndrome (EDS)
15-05-2020
Overall
5
Explanation
5
Bedside Manner
5

Great consultation over the phone, Dr. Brennan was very detailed and allowed time for questions. I also got a digital consultation report within the day for my records.

Patient seen for:
Genetic Consultation
14-05-2020
Overall
5
Explanation
5
Bedside Manner
5

Couldn’t recommend highly enough. We had an extremely complex issue which Dr. Brennan explained throughly to use, and was followed up with a comprehensive report. We didn’t feel rushed, and had enough time to ask many, many, questions.

Patient seen for:
Genetic Consultation
Male Infertility
13-05-2020
Overall
5
Explanation
5
Bedside Manner
5

Great and informative appointment. Dr Brennan was extremely helpful, answered all my questions and provided great assurance throughout the appointment and testing process.

Patient seen for:
Clinical Genetics
24-02-2020
Overall
5
Explanation
5
Bedside Manner
5

My wife and I booked an appointment with Dr Brennan who made himself available at a convenient time for us. He was very clear in his explanation of our particular issue and has been very helpful in his follow up with the next steps. I would certainly recommend Dr Brennan

Patient seen for:
Clinical Genetics
29-01-2020
Overall
5
Explanation
5
Bedside Manner
5

Although I had a short interaction with Dr. Brennan I found his explanation very clear. He was very interested in my family history and my concern relating to breast cancer risk. He presented to me with a graphical support the various genes which may impact the development of risk cancer and recommended, based on his experience, the best test that I should take. I felt very comfortable in his presence and trust his experience and knowledge in the matter.

Patient seen for:
Clinical Genetics
24-01-2020
Overall
5
Explanation
5
Bedside Manner
5

Extremely professional and ensured the patient was at ease through out the consultation. Prompt with intimating results, and very comprehensive in his consultation. I would strongly recommend Dr Brennan.

Patient seen for:
Clinical Genetics
09-12-2019
Overall
5
Explanation
5
Bedside Manner
5

Doctor Brennan has been very helpful throughout the entire diagnose period. His follow up and explanation have been crystal clear and meant a lot to us while we going through that time. Thank you again for your expertise and kind thought!

09-12-2019
Overall
5
Explanation
5
Bedside Manner
5

We had a consultation with Dr Brennan regarding a hereditary genetic condition affecting our family. He provided a very clear explanation of the issues and was clearly very knowledgeable in the field. He had a very reassuring and patient manner. He offered plenty of time and opportunity for questions. He was extremely quick and responsive to all our enquiries and gave some practical advice and appropriate guidance about the issues of testing. We felt very confident in all aspects of his care and would have no doubt in highly recommending him to others.

Patient seen for:
Genetic Consultation
25-11-2019
Overall
5
Explanation
5
Bedside Manner
5

I was seen for a very rare disease Looking forward to have the diagnosis

25-10-2019
Overall
5
Explanation
5
Bedside Manner
5

Dr Brennan was so reassuring thoughout the whole of our chat. He made me feel a lot less stressed and ensured I was ok with what he was saying. I loved that he asked my opinion and how I felt instead of just giving me information. He gave me a perspective on the situation that within a stressful time I wasn’t able to imagine. Amazing help and professionalism

Patient seen for:
Genetic Consultation
11-10-2019
Overall
5
Explanation
5
Bedside Manner
5

Dr Brennan was very polite and welcoming and made our baby feel at ease. He has a very warm manner which I personally think is vital when dealing with children and he is softly spoken also; so he is not in any way intimidating to young children. He took the time to listen to our concerns and didn’t make us feel we were imagining there was a medical issue which was how we were made to feel when speaking to an NHS doctor. He was efficient and I note in his follow up report he had taken on board everything we had mentioned. Very happy with the service.

Patient seen for:
Genetic Procedures
11-10-2019
Overall
5
Explanation
5
Bedside Manner
5

I took myself and my two children along to see Dr Brennan at the international gene clinic in Newcastle. I myself, had been misdiagnosed for many years and have suffered many complications along the way. I noticed my children were beginning to suffer similar symptoms as myself. I had a scan which found a hindbrain hernia which could be connected to a connective tissue disorder, that's when I set off on my journey to find someone who could give me the correct diagnosis along with my children. I chose Dr Brennan as he highly recommended, he has a lovely way in which he listens to your problems, he is very thorough and explains in detail why you could be experiencing certain symptoms and how certain systems in the body are affected. It was a pleasure for me and my family to see Dr Brennan and I would highly recommend him as he diagnosed each of us and has guided us in the right direction of Drs who will be able to help manage our condition.Many Thanks

Patient seen for:
hEDS
10-10-2019
Overall
5
Explanation
5
Bedside Manner
5

Thoughtful and clear.

Patient seen for:
Dhlers-Danlos Syndrome (EDS)
08-10-2019
Overall
5
Explanation
5
Bedside Manner
5

It gave me alot of answers that I have been searching for. I would recommend a consultation in a heart beat if you need answers

Patient seen for:
Hypermobility Syndrome
08-10-2019
Overall
5
Explanation
5
Bedside Manner
5

My first meeting with Dr Brennan was excellent. He was easy to talk to, explained things very well and seemed to be extremely thorough and knowledgeable. He put both my son and me at ease which wasn’t easy given the circumstances. I’ve been looking for a specialist in this area of medicine and I feel confident that Dr Brennan will be able to provide answers.

Patient seen for:
Genetic Procedures
24-09-2019
Overall
5
Explanation
5
Bedside Manner
5

Dr Brennan was very understanding about the reasons why I had sought advice at the clinic. His knowledge of connective tissue/hypermobility disorders and experience of patients with these issues was evident and as a result he has provided me with good information and recommendations regarding my own diagnosis. A worthwhile appointment.

Patient seen for:
Hypermobility Syndrome
19-09-2019
Overall
5
Explanation
5
Bedside Manner
5

Dr Brennan was welcoming and put us at our ease. He was very thorough, explained things clearly and took the time to listen. I would definitely recommend Dr Brennan to others.

Patient seen for:
Hypermobile Ehlers-Danlos Syndrome
11-09-2019
Overall
5
Explanation
5
Bedside Manner
5

Dr Brennan is very good, I saw him with my ten year old son, we both have hEDS. He gave us lots of time to explain our situation, listened to us and helped us to feel at ease. He explained everything clearly and gave good advice for future treatment. I would absolutely recommend him.

Patient seen for:
hEDS
11-09-2019
Overall
5
Explanation
5
Bedside Manner
5

Fantastic, compassionate and fully explained everything. Asked many questions, answered even more. Lifelong queries finally been explained in detail....can move onwards and upwards after 3 years of being passed from pillar to post Dr Brennan hit the nail on the head. Highly recommend, worth travelling to see.

Patient seen for:
Dhlers-Danlos Syndrome (EDS)
11-09-2019
Overall
5
Explanation
5
Bedside Manner
5

Dr Brennan put me at ease from the moment I walked through his door. He listened when I spoke, and was very thorough going through my past history. He examined me and confirmed a diagnosis of hEDS. I have been trying to get an answer for my myriad symptoms for over 27 years. I cannot tell you how incredible it is to finally have the answer and to know that there is someone in my corner now. He sent a very thorough report to me, just days after the consultation which had recommendations for my GP going forward. I cannot thank him or praise him enough.

Patient seen for:
Hyypermobile Ehler's Danlos
21-08-2019
Overall
5
Explanation
5
Bedside Manner
5

Dr. Brennan has a lovely mild manner and dealt beautifully with my 7 yo daughter - quick to make her comfortable with some chat and jokes! He was extremely thorough and knowledgeable and diagnosed hEDS for my daughter and I in 1 appointment. He provided our diagnostic letters, which were some of the best clinician letters I've ever seen, in under 48 hrs. Time will tell what happens with trying to get local medics to accept this diagnosis but Dr. Brennan definitely knows his stuff and provides an excellent service.

Patient seen for:
Dhlers-Danlos Syndrome (EDS)
21-08-2019
Overall
5
Explanation
5
Bedside Manner
5

My experience with Dr Brennan was fantastic. He was extremely welcoming, kind and gentle. He didn't judge and I felt as if I could discuss all my symptoms. In the past I have been dismissed as a hypochondriac when and I was very nervous before the appointment that it would happen again, but I shouldn't have worried. He explained all the issues weren't just in my head and was also really knowledgeable about different ways apart from the joints and ligaments, connective tissues disorders seem to manifest and gave advice on how to deal with the condition in my everyday life which I didn't know how to before.

Patient seen for:
Hypermobile Ehlers-Danlos Syndrome
20-08-2019
Overall
5
Explanation
5
Bedside Manner
5

We left with a much better understanding of the challenges facing our daughter. We felt comfortable asking many questions. All of which were answered patiently where possible. The session was greatly appreciated.

Patient seen for:
Clinical Genetics
12-08-2019
Overall
5
Explanation
5
Bedside Manner
5

Dr. Brennan is a fantastic doctor and was amazing with our youngest as she normally will shy away from doctors, but Paul's manner and communication was excellent and he was able to complete his examination.

Patient seen for:
Ehlers-Danloss Test
09-08-2019
Overall
5
Explanation
5
Bedside Manner
5

He is very knowledgable about connective tissue disorders, something that is very difficult to find. He takes a lot of time to go through all history with you and explain what it might indicate. I feel like he has taken my symptoms more seriously than most doctors I have seen for this the past 15 years.

Patient seen for:
Ehlers-Danlos syndrome
18-07-2019
Overall
5
Explanation
5
Bedside Manner
5

Dr Brennan was very clear in his explanation of my condition, the implications and now to manage it. He was very knowledgeable about the more cutting edge science around gut health and connection to hypermobility. I wouldn’t hesitate to recommend him!

Patient seen for:
Hypermobility Syndrome
13-07-2019
Overall
5
Explanation
5
Bedside Manner
5

Dr Paul Brennan was understanding during consultation. I felt Dr Brennan went above and beyond for my family and myself. He reassured us everything will be fine no matter the result.

Patient seen for:
Clinical Genetics
12-07-2019
Overall
5
Explanation
5
Bedside Manner
5

He listened. He did not judge. He explained why my symptoms are not made up. I felt very at ease and able to discuss my symptoms without feeling like a hypochondriac!

Patient seen for:
Heds
11-07-2019
Overall
5
Explanation
5
Bedside Manner
5

Dr Paul Brennan is, in my experience and opinion, the best consultant I have had thus far. I felt at ease through what would have been a very stressful and difficult experience had it not been for Paul's clear advice and friendly and approachable manner. Paul communicated with me regularly and in a clear and concise way that avoided some of the quite confusing medical jargon I have experienced from other consultants in the past. I feel I have been supported throughout the process of genetic testing in a way which did not dismiss my worries and concerns about my family history of cancer, and I feel that all possible routes have been taken to finding out the information I needed. I would highly recommend Dr Brennan as a fantastic consultant.

Patient seen for:
Genetic Consultation
11-07-2019
Overall
5
Explanation
5
Bedside Manner
5

Dr Paul Brennan was extremely welcoming and made us feel at ease. He was very thorough in his background questioning taking time to probe further where necessary. After a thorough examination he took time to explain the diagnosis and condition and treatments that may be available through NHS and the private sector. I would not hesitate to recommend him to others in the Scottish region as he was very good with both myself and my son.

Patient seen for:
Ehlers Danlos Syndrome
10-07-2019
Overall
5
Explanation
5
Bedside Manner
5

Our assessment was excellent Dr Brennan was very softly spoken, calming and listened to our concerns he also spoke to my son directly in the same manner, he wasn’t put off by his behaviour and explained his thought process in detail but also in simple terms. The clinic is in a great location and the service on arrival was excellent and surroundings comfortable

Patient seen for:
ehlers-danlos syndrome (EDS)
12-06-2019
Overall
5
Explanation
5
Bedside Manner
5

A true doctor. Knowledgeable, kind, compassionate. He took the time to really listen. We need more doctors like dr Brennan in this world. Thank you x

Patient seen for:
ehlers-danlos syndrome (EDS)
11-06-2019
Overall
5
Explanation
5
Bedside Manner
5

Excellant consultant. Fast diagnosis and was very supportive of everything that I am dealing with as a result of the Ehlers Danlos Syndrome

Patient seen for:
ehlers-danlos syndrome (EDS)
10-06-2019
Overall
5
Explanation
5
Bedside Manner
5

Hugely personable and knowledgeable- Pits patients at ease, nothing was rushed and we left with hope!

10-06-2019
Overall
5
Explanation
5
Bedside Manner
5

I’ve been seeing the lovely Dr Brennan for the past 16 years. He has been a constant support to myself and my family. My condition has been very difficult throughout the years but Dr Brennan has never given up on me. He is such a lovely, genuine, gentle man with a wealth of knowledge. At the very beginning of my diagnosis, he was the only person that took me seriously enough to look into what was going on with me. I honestly believe that if it wasn’t for him, I might not be here now. I was walking around with a wrong diagnosis and a dilated aorta. I can safely say that my family and I owe so much to Paul. I just hope he never retires! I’d be lost without him!

Patient seen for:
Marfan Syndrome
ehlers-danlos syndrome (EDS)
Hypermobility Syndrome
23-05-2019
Overall
5
Explanation
5
Bedside Manner
5

I’ve been seeing the lovely Dr Brennan for the past 16 years. He has been a constant support to myself and my family. My condition has been very difficult throughout the years but Dr Brennan has never given up on me. He is such a lovely, genuine, gentle man with a wealth of knowledge. At the very beginning of my diagnosis, he was the only person that took me seriously enough to look into what was going on with me. I honestly believe that if it wasn’t for him, I might not be here now. I was walking around with a wrong diagnosis and a dilated aorta. I can safely say that my family and I owe so much to Paul. I just hope he never retires! I’d be lost without him!

Patient seen for:
Marfan Syndrome
ehlers-danlos syndrome (EDS)
Hypermobility Syndrome
23-05-2019
Overall
5
Explanation
5
Bedside Manner
5

I had a private consultation with Dr Paul Brennan. He was calm, considerate, and understanding. He took the time to consider the list of symptoms I gave to him prior the the consultation, to explore differential diagnoses, which I greatly appreciate. I was offered swift genetic testing and he informed me about what the results would mean, and possible treatments. Communication outside of the consultation has been great.

Patient seen for:
Genetic Consultation
09-05-2019
Overall
5
Explanation
5
Bedside Manner
5

Dr Brennan was a lovely guy

Patient seen for:
Breast Cancer
09-05-2019
Overall
5
Explanation
5
Bedside Manner
5

Had a appointment for my young daughter and myself, my daughter was feeling quite nervous but that soon went as the minute we entered the room we were put at ease, the appointment was very relaxed and he listened to everything we said and he explained things clearly, he explained everything would be put in writing to me as there is a lot to take in. I would highly recommend

06-05-2019